The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
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A phase transition enhances the catalytic activity of SARM1, an NAD+ glycohydrolase involved in neurodegeneration
Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
Dr. Jing Yang's Lab: The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative Sarm1 - IDG/McGovern Institute for Brain Research at PKU
SARM1 activation and its downstream pathways are distinct in neuronal compartments
NAD+ Inhibits Protein that Promotes Neuron Degeneration
SARM1 activation and its downstream pathways are distinct in neuronal compartments
Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease - ScienceDirect
Biology, Free Full-Text
Frontiers A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism - ScienceDirect
Frontiers Multifaceted roles of SARM1 in axon degeneration and signaling
A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1
Early loss of endogenous NAD+ following rotenone treatment leads to mitochondrial dysfunction and Sarm1 induction that is ameliorated by PARP inhibition - Sarkar - 2023 - The FEBS Journal - Wiley Online Library
The curious case of SARM1: Dr. Jekyll and Mr. Hyde in cell death and immunity? - Sarkar - 2023 - The FEBS Journal - Wiley Online Library
